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The mechanical allodynia, thermal hyperalgesia, blood glucose, advanced glycation end products (AGEs), plasma HbA1C, and spinal inflammatory markers were evaluated

Maybe the side effects became unbearable

[0021] In some particular embodiments of the present invention, in the preparation method, for Boc-His(Trt)-OH, the coupling is performed by a B+A+C system

The primary mechanism of action involves binding to GLP-1 receptors on pancreatic beta cells, which stimulates glucose-dependent insulin secretion

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